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GLP-1 plays a key role in gut-brain communication

It was bought by Novo Nordisk (of Ozempic aka Semaglutide fame) who started a large phase 3 trial (CLARION CKD) for hypertension in CKD, enrolling over 600 patients

Semaglutide is not contraindicated in inflammatory bowel disease, but patients with ulcerative colitis or Crohn's disease should discuss their condition with their healthcare provider before starting treatment

Manijeh Kamyar, a maternal-fetal medicine specialist and OB-GYN in Las Vegas, Nevada, says patients usually tell her no one has discussed the risks of Ozempic with them

While convenient, these services typically charge $200-$400+ monthly, provide limited personalized medical supervision, offer no local support or accountability, and may source from compounding pharmacies of uncertain quality

Appetite stimulation Investigated in preclinical work for its strong ghrelin-receptor-driven hunger signaling